论文部分内容阅读
目的:探讨急性脑血管疾病(ACVD)并急性肾损伤(AKI)的相关影响因素,为临床合理治疗ACVD,预防AKI的发生提供一定的理论依据。方法:应用医院网络信息系统筛选出2009年10月～2012年2月ACVD并AKI患者,回顾分析ACVD并AKI患者的发病率、并发症及相关检测指标,用Logistic回归分析ACVD并AKI的病因和相关因素。结果:ACVD并AKI的总发病率为10.28%,ACVD并AKI患者均合并1种或以上其他疾病,Logistic回归分析提示感染是AKI最常见的病因。单因素回归分析显示年龄、血肌酐(Scr)基础值、血尿素氮(BUN)基础值、二氧化碳结合力(CO2CP)基础值、Scr峰值、BUN峰值、血尿酸(UA)峰值、血清白蛋白(ALB)(P<0.05)是ACVD并发AKI的影响因素,进行多因素logistic逐步回归分析,得出Scr峰值是ACVD并AKI的最重要因素。结论:ACVD患者可并发AKI,尤其是在ICH患者中易发生。感染是ACVD并发AKI的常见病因,而年龄、Scr基础值、BUN基础值、CO2CP基础值、Scr峰值、BUN峰值、UA峰值、ALB是ACVD并AKI的有密切关系,临床上需要重视上述诸项相关因素。
Objective: To investigate the related factors of acute cerebrovascular disease (ACVD) and acute kidney injury (AKI), and to provide some theoretical basis for clinical treatment of ACVD and prevention of AKI. Methods: The hospital ACVD and AKI patients were screened from October 2009 to February 2012 by hospital network information system. The incidence, complications and related indicators of ACVD and AKI were retrospectively analyzed. Logistic regression analysis was used to analyze the etiology and prognosis of ACVD and AKI relevant factor. Results: The overall incidence of ACVD and AKI was 10.28%. Other ACVD and AKI patients were complicated by one or more other diseases. Logistic regression analysis indicated that infection was the most common cause of AKI. Univariate regression analysis showed that age, basal serum creatinine (Scr), basal blood urea nitrogen (BUN), basal carbon dioxide binding (CO2CP), Scr peak, BUN peak, UA peak, serum albumin ALB) (P <0.05) were the influencing factors of ACVD complicated with AKI. Multivariate logistic stepwise regression analysis showed that Scr peak was the most important factor of ACVD and AKI. Conclusions: Patients with ACVD may be complicated by AKI, especially in patients with ICH. Infection is a common cause of ACVD complicated with AKI. However, age, Scr basal value, BUN basal value, CO2CP basal value, Scr peak, BUN peak value, UA peak value and ALB are closely related to ACVD and AKI. Clinically, relevant factor.