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作者对1686例肺结核,脊柱结核及结核性脑膜炎(简称结脑)的病人进行了短化的临床研究,并总结其对肝脏的毒性反应。病人年龄:肺结核病人12岁以上,结脑1—12岁,脊柱结核年龄不限。化疗方案及肝毒性反应脊柱结核:Ⅰ组97例病人用根治术和6RH_7(R 10-15mg/kg 体重,H 6mg/kg、最大量300mg)治疗,发生黄疸17例(18％);Ⅱ组194例只用6RH_7(剂量同前)治疗,发生黄疸20例(10％),
The authors conducted a short clinical study of 1686 patients with tuberculosis, spinal tuberculosis and tuberculous meningitis (referred to as tuberculous meningitis), and summarized their toxic reactions to the liver. Patient’s age: Tuberculosis patients over 12 years old, knot brain 1-12 years old, spinal tuberculosis age is not limited. Chemotherapy regimens and hepatotoxicity in patients with spinal tuberculosis: Group Ⅰ 97 patients were treated with radical operation and 6RH7 (R 10-15mg / kg body weight, H 6mg / kg, maximum 300mg), 17 cases (18%) had jaundice; Group Ⅱ 194 cases only 6RH_7 (the same dose) treatment, jaundice occurred in 20 cases (10%),