阿片成瘾者２５０例（男性２２２例，女性２８例，年龄３０±ｓ５ａ）应用山莨菪碱０．５－２ｍｇ／（ｋｇ·ｄ），分２－３次加入１０％葡萄糖２５０ｍＬ或５％葡萄糖生理盐水５００ｍＬ静脉滴注；东莨菪碱０．０２－０．０３ｍｇ／ｋｇ加入１０％葡萄糖２５０ｍＬ静脉滴注１次，必要时对重患者追加１次，疗程５－７ｄ。结果戒断症状均有改善（Ｐ＜０．０１），２７例需加用羟丁酸钠。不良反应轻，可作为阿片瘾者的脱瘾药物。＊Ｐ＜０．０１。碱确能解除阿片药物戒断症状。其对阿片戒断症状缓解时间在治疗４－５ｄ后，强烈觅药渴求也随之逐渐消失。１５０例（６０％）要求进食，１７５例（７０％）仍需借助安眠药睡眠。另６５例（２６％）戒断症状阵发性发作，每次持续０．５－１ｈ，症状轻重不一，轻者流泪、全身弥漫性疼痛，重者焦躁不安、心中猫抓虫咬样难受，甚至想自残，可配合艾司唑仑３－４ｍｇ／ｄ，ｐｏ或氯硝西泮６－１０ｍｇ／ｄ，ｐｏ；也可用氯硝西泮１－２ｍｇ／次，ｉｍ，每日２－３次；针刺胃俞、脾俞、中脘、足三里、印堂、太阳、百会、内关、合谷、命门、夹脊和肾俞穴位，根据临床症状任选其中３－５个穴位进行治疗或心理治疗能快速减轻患者戒断症状。治程中２７例（１０．８％）重? 250 opiate addicts (222 males and 28 females, age 30 ± s5a) were anesthetized with anisodamine 0.5-2 mg / (kg · d), and 10% dextrose 250 mL or 5% dextrose Saline 500mL intravenous drip; scopolamine 0.02-0.03mg / kg add 10% glucose 250mL intravenous infusion 1, if necessary, additional patients with heavy 1, the course of treatment 5-7d. Results Withdrawal symptoms were improved (P <0.01), 27 cases need to add sodium oxybate. Adverse reactions are mild and can be used as addicts for opiate addicts. * P <0.01. Alkali can really lift the withdrawal symptoms of opiate drugs. The opiate withdrawal symptoms alleviate the time in the treatment of 4-5d, a strong desire to find medicine also will gradually disappear. 150 (60%) require eating, 175 (70%) still need to sleep with sleeping pills. The other 65 cases (26%) with paroxysmal episodes of withdrawal symptoms, each lasting 0.5-1h, the symptoms vary in severity, the light of the tears, systemic diffuse pain, severe restlessness, the hearts of cat catching insects bitter uncomfortable , Or even want to self-mutilation, with 3-4mg / of eszolam, po or clonazepam 6-10mg / d, po; also available clonazepam 1-2mg / time, im 2-3 Acupuncture stomach, spleen, Zhongli, Zusanli, Yintang, the sun, Baihui, Neiguan, Hegu, life gate, Jiaji and Shenshu acupuncture points, according to the clinical symptoms of optional 3-5 acupuncture points Treatment or psychological treatment can quickly reduce withdrawal symptoms in patients. Treatment of 27 cases (10.8%) weight?