Botanical Therapeutics for Parkinson's Disease

来源 :中国结合医学杂志(英文版) | 被引量 : 0次 | 上传用户:flexrhythm
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Parkinson\'s disease (PD) was first formally described by James Parkinson in 1817,but the shaking of limbs was described in the literature of several ancient civilizations,such as ancient Chinese civilization and ancient Indian civilization.Historically,botanical drugs were used as the main source for the treatment of such kind of disorders.In Western countries,plant extracts also occupied an important place in the earlier medications of PD.With the adventure of synthetic drugs,the role of plant-derived drugs in management of PD has been diminished.Nowadays,there is still no cure for PD,dopaminergic (DA) medication is the treatment of choice,which is just designed to ameliorate symptoms of PD,and long-term use of DA medication will result in reduced efficacy and severe adverse reactions.It is necessary to explore new methods for the treatment of PD.Chinese medicine (CM) developed a holistic and unique theoretical system,and botanical drugs are widely used in practice for more than two millennia.Modern pharmacological studies have proved that Chinese herbs have potential therapeutic effects on PD,such as enhancing neurotrophic activity,clearing protein aggregates,regulating neuroinflammation,etc.All the advances provide us with hope for developing CM as a mainstream medication for treating PD.
其他文献
Objective:To investigate the inhibitory effect of Linggui Zhugan Decoction (LZD,苓桂术甘汤)on the ventricular remodeling (VR) after acute myocardial infarction (AMI) and related mRNA and proteins expression in transforming growth factor-beta 1 (TGF-β1)/Smad si
Objective:To observe the intervention effects of Tiaobu Xinshen Recipe(调补心肾方,TXR) on patients with mild cognitive impairment caused by Alzheimer\'s disease (MCI-AD).Methods:Totally 88 MCI-AD patients with syndrome of Xin (Heart) and Shen (Kidney) defici
Primary Sj(o)gren\'s syndrome (pSS) is a chronic autoimmune disease with a long duration of illness,for which there is no cure.Patients often suffer from anxiety and depression due to various reasons,exhibiting a decline in their quality of life.Chinese
Objective: To investigate the therapeutic and synergistic effects of QHC (combination of quercetin (Q),hirudin (H) and cinnamaldehyd (C)) on Schwann cell differentiation and myelination against high glucose (HG) induced injury.Methods: Primary-culture Sch
Traditional glucose-lowering chemical agents,including various types of insulin and insulin secretagogues,insulin sensitizers,gliptins,etc.,are based on diabetic pathogenesis of insulin resistance (IR) and islet insufficiency.Numerous evidence-based medic
Objective:To evaluate whether low-frequency ultrasound-facilitated transdermal delivery of a Chinese medicine (CM) formula could improve the efficacy of intrapleural administration of interleukin-2 (IL-2)in treatment of malignant pleural effusion (MPE).Me
Objective:To study the effects of Prunella vulgaris polysaccharide (PVP) on human breast carcinoma-associated fibroblasts (CAFs).Method:Cell viability was detected by 3-[4,5-dimethylthiazol-2-yl]-2,5-(3-carboxymethoxyphenyl)-2-4-sulfophenyl)-2H-tetrazoliu
Background: The incidence of cognitive impairment (CI) is gradually increasing,which has attracted more attention from medical researchers worldwide.Definitive mechanisms of pathogenesis remain elusive,and there are few medications that have been proven e
Objective:To determine the effects of Hydrangeae Dulcis Folium (EHDF) on physical stress,changes in the whole-body cortisol level and behaviour in zebrafish (Danio rerio).Methods:One hundred and seventy-four fish were randomly divided into 4 [adrenocortic
Objective:To investigate the effect of hydrogen-rich Korean Red Ginseng (KRG) water (HRGW) mixture on the spermatogenesis and sperm motility of mice of different ages.Methods:Eighty young (3 month-old) and aged (12 month-old) male mice were randomly assig