抗纤维化治疗对乙肝肝纤维化患者的临床作用

来源 :现代医学与健康研究 | 被引量 : 0次 | 上传用户:qq6563187
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目的探讨在乙肝肝纤维化患者中实施抗纤维化治疗的作用及临床意义。方法选取92例乙肝肝纤维化患者进行分组研究,对照组实施单纯重组人干扰素γ抗纤维化治疗,观察组在对照组的治疗基础上联合盐酸川芎嗪注射液治疗。比较两组临床疗效、肝功能、乙肝病毒的脱氧核糖核酸(HBV-DNA)、治疗前后血清透明质酸(HA)、Ⅲ型前胶原(PⅢP)、粘连蛋白(FN)和Ⅳ型胶原(IV-C)水平变化。结果观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);观察组及对照组肝功能均有所恢复,HBV-DNA均下降,但两组比较差异
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