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目的掌握不同厂家氯硝柳胺与烟酰苯胺复配的灭螺效果。方法将氯硝柳胺与烟酰苯胺按1∶1的比例进行复配形成复合物(简称氯烟复合物),在室内进行浸杀和喷洒灭螺实验并观察钉螺触药上爬及鱼类急性毒性情况。结果在室温23～25℃条件下,采用0.2mg/L氯烟复合物,室内浸泡48h,3个厂家氯烟复合物淮南组、吴江组和四川组的钉螺死亡率分别为93.3%、94.7%和95.4%。采用0.4g/m氯烟复合物,室内喷洒248h,3个厂家氯烟复合物淮南组、吴江组和四川组的钉螺死亡率分别为97%、96%和96%。钉螺接触氯烟复合物的上爬率比烟酰苯胺下降71.9%,2组钉螺上爬率差异有统计学意义(P<0.01)。对鱼的急性毒性,氯烟复合物比氯硝柳胺下降50%左右。结论不同厂家氯硝柳胺和烟酰苯胺通过复配后均可获得增效灭螺的作用。
Objective To master the snail-killing effects of niclosamide and nicotinamide mixed with different manufacturers. Methods Niclosamide and nicotinamide were compounded in the ratio of 1: 1 to form compound (referred to as chlorine and smoke compound), immersed and spray molluscicidal experiment indoors, and observed snail crawling and fish Acute toxicity. Results The mortality rates of snail in Huainan, Wujiang and Sichuan groups were 93.3% and 94.7%, respectively, at the ambient temperature of 23-25 ℃ with 0.2 mg / L chlorine compound and 48h indoor immersion. And 95.4%. The mortality of snail in Huainan, Wujiang and Sichuan groups was 97%, 96% and 96% respectively with 0.4g / m chlorine compound and 248h indoor spraying. Climbing rate of snail contact with chlorine smoke compound was 71.9% lower than that of nicotinamide, and there was significant difference in climbing rate of snail between two groups (P <0.01). Acute toxicity to fish, chlorine smoke compound than niclosamide decreased by about 50%. Conclusion Different manufacturers of niclosamide and nicotinamide aniline can be synergistic through snailing effect.