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目的 探讨经腹彩色多普勒超声观察血管定位和血流曲线形态对诊断卵巢恶性肿瘤的价值。方法 使用彩色多普勒超声检查 2 8例卵巢恶性肿瘤和 41例良性肿瘤 ,测定肿瘤的血管定位、舒张期切迹、搏动指数(PI)和阻力指数 (RI) ,将PI和RI与术后病理组织学结果对照 ,以此预测卵巢恶性肿瘤的灵敏性、特异性。结果 卵巢恶性肿瘤PI是 0 5 4± 0 15 ,良性为 1 48± 0 6 5 ;恶性肿瘤RI为 0 40± 0 0 94,良性为 0 85± 0 0 99(P<0 0 0 1)。卵巢恶性肿瘤 10 0 %可见血管 ,并定位于肿瘤中心 (96 4% ) ,92 9%无舒张期切迹 ;良性肿瘤46 3 %可见血管 ,并定位于肿瘤周边 (94 7% ) ,89 5 %可见舒张期切迹。以 0 76为PI界值 ,其预测卵巢恶性肿瘤的敏感性、特异性及阳性和阴性预测率分别为 92 9%、94 7%、96 3 %和 90 0 % ;以 0 5 6为RI界值 ,其敏感性、特异性及阳性和阴性预测率分别为 89 3 %、94 7%、96 2 %和 85 7%。结论 经腹彩色多普勒超声观察血管定位、搏动指数、阻力指数和舒张期切迹是鉴别卵巢良恶性肿瘤有参考价值的方法之一
Objective To investigate the value of transabdominal color Doppler ultrasonography in the diagnosis of ovarian cancer. Methods Twenty eight cases of ovarian cancer and 41 benign tumors were examined by color Doppler sonography. The vascular location, diastolic notch, pulsatility index (PI) and resistance index (RI) were measured. The PI and RI were compared with those after operation Histopathological results of control, in order to predict the sensitivity and specificity of ovarian cancer. Results The PI of ovarian cancer was 0 54 ± 0 15 and the benignity was 1 48 ± 0 65. The RI of the malignant tumor was 0 40 ± 0 0 94 and the benign was 0 85 ± 0 0 99 (P 0 01 0). Ovarian malignancies were found in 100% of the vessels and located in the center of the tumor (96.4%) with 92.9% non-diastolic notch. The benign tumors were visible in 46.3% of the vessels and located in the periphery of the tumor (94.7%), 89.5 % Visible diastolic notch. The sensitivity, specificity, and positive and negative predictive rates of ovarian cancer were 92 9%, 94 7%, 96 3% and 90 0% respectively with 0 76 as the cut-off point for PI. The sensitivity, specificity, and positive and negative predictive values were 89 3%, 94 7%, 96 2% and 85 7%, respectively. Conclusions Transabdominal color Doppler ultrasound can be used as a reference to identify benign and malignant ovarian tumors by observing vascular location, pulsatility index, resistance index and diastolic notch