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目的探讨应用头孢菌素类药物后双硫仑样反应发生的原因及急诊处理程序。方法对12例双硫仑反应患者进行回顾性分析。结果来院的12例双硫仑样反应患者抢救成功率100.0%,其发生的原因与中国社会饮酒风俗、医务人员宣教不到位、群众重视程度不够有关。结论政府相关部门应加强宣教,改变不良社会风气;医务工作者应加强健康教育并做好用药前、用药后的宣教。发生双硫仑样反应征象后及时赴医院就诊,能有效减少双硫仑样反应的发生率及不良后果,避免病死的发生。
Objective To investigate the causes of disulfiram-like reaction and the emergency treatment procedure after cephalosporins treatment. Methods Twelve patients with disulfiram reaction were retrospectively analyzed. Results The success rate of salvage in 12 patients with disulfiram-like response to hospital was 100.0%. The reason for the rescue was related to the drinking habits of Chinese society, the inadequate education of medical personnel, and the insufficient attention of the masses. Conclusion The relevant government departments should step up their propaganda and education to change the negative social ethos. Medical workers should strengthen their health education and do the pre-medication and post-medication education. Symptoms of disulfiram-like occurred in a timely manner to the hospital for treatment, can effectively reduce the incidence of disulfiram-like reactions and adverse consequences, to avoid the occurrence of disease.