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目的分析肝硬化不同肝功能分级患者血栓弹力图(thromboelastography,TEG)表现。方法肝硬化患者107例,肝功能Child A级36例为Child A级组,Child B级38例为Child B级组,Child C级33例为Child C级组,监测3组TEG并比较分析。结果 Child C级组TEG中R值[(6.20±1.88)min]、K值[(4.10±2.03)min]高于Child A级组[(4.45±1.21)、(2.37±1.58)min]和Child B级组[(5.12±1.56)、(3.25±1.02)min],LY30(0)、MA[(25.20±6.51)mm]和Angle[(41.42±10.27)deg)]低于Child A级组[(0.80±0.11)%、(59.30±7.30)mm、(62.67±10.20)deg]和Child B级组[(0.60±0.17)%、(36.80±5.84)mm、(50.87±9.68)deg],差异均有统计学意义(P<0.05)。结论 TEG可反映肝硬化患者凝血紊乱状况,TEG参数异常间接反映了病情严重程度。
Objective To analyze the manifestations of thromboelastography (TEG) in patients with different grades of liver cirrhosis. Methods A total of 107 cirrhotic patients were enrolled. Totally 36 children with Child A grade were Child A class, 38 Child C class were Child B class, and Child C class 33 Child C class. TEG was monitored and compared. Results In Child C group, the R value [(6.20 ± 1.88) min] and K (4.10 ± 2.03) min in TEG were higher than those in Child A group [(4.45 ± 1.21) and (2.37 ± 1.58) min] The levels of LY30 (0), MA [(25.20 ± 6.51) mm] and Angle [(41.42 ± 10.27) deg) in group B were significantly lower than those in Child A group [(5.12 ± 1.56), (3.25 ± 1.02) (0.80 ± 0.11)%, (59.30 ± 7.30) mm, (62.67 ± 10.20) deg and Child B group (0.60 ± 0.17)%, (36.80 ± 5.84) mm and (50.87 ± 9.68) All were statistically significant (P <0.05). Conclusion TEG can reflect the coagulopathy in patients with cirrhosis. The abnormal TEG parameters indirectly reflect the severity of the disease.