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目的对维生素B12治疗小儿水痘疗效进行分析。方法病例分为治疗组与对照组。治疗组:在对症治疗、龙胆紫外涂等一般治疗基础上加用维生素B12针剂,剂量500ug/d,每日一次,连用3～5天;对照组在治疗组基础上加用利巴韦林,剂量为10～15mg/(kg·d),肌注,每日二次,连用3～5天。结果治疗组退热时间、抑制疱疹出现时间及疱疹基本结痂时间均优于对照组,统计学上差异有显著性(P<0.01);在显效率、有效率方面治疗组明显优于对照组,差异有显著性(P<0.05)。结论维生素B12治疗水痘,可迅速控制病情,与利巴韦林比较,在退热时间、疱疹结痂时间均明显缩短,而且药物性能安全,无不良反应,是一种安全有效的治疗水痘药物。
Objective To analyze the curative effect of vitamin B12 on chickenpox in children. Methods The cases were divided into treatment group and control group. Treatment group: In the symptomatic treatment, gentian UV coating and other general treatment based on the use of vitamin B12 injection, the dose of 500ug / d, once daily, once every 3 to 5 days; the control group on the basis of the treatment group plus ribavirin , The dose of 10 ~ 15mg / (kg · d), intramuscular injection, twice daily, once every 3 to 5 days. Results The antipyretic time, the time of herpes simplex suppression and the basic scab time of the herpes in the treatment group were all better than those in the control group (P <0.01). The treatment group was significantly better than the control group in the markedly effective rate , The difference was significant (P <0.05). Conclusion Vitamin B12 treatment of chicken pox can be quickly controlled the condition, compared with ribavirin, antipyretic time, herpes scab time were significantly shorter, and the drug performance is safe, no adverse reactions, is a safe and effective treatment of chickenpox drugs.