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新研究显示:将阿司匹林固新研究显示:将阿司匹林键合到顺铂上,可能在癌症治疗中克服顺铂耐药细胞的耐药性。该研究成果发表于《Chemical Communications》,并被《Chemistry World》新闻报道。顺铂以及其他铂类化疗药物,常被用来治疗多种癌症,包括睾丸癌、卵巢癌、肺癌和膀胱癌,顺铂也因此被称为“癌症中的青霉素”。然而,获得性耐药性限制了顺铂在临床上的使用。关于顺铂的耐药机制已有系统的研究,但目前仍然缺乏有效的方法来克服或逆转耐药性。
New study shows: Aspirin new research shows that: Aspirin bonding to cisplatin, may be in the treatment of cancer resistance to cisplatin-resistant cells. The research was published in Chemical Communications and was reported by Chemistry World. Cisplatin and other platinum-based chemotherapy drugs are often used to treat a variety of cancers, including testicular cancer, ovarian cancer, lung cancer and bladder cancer. Cisplatin is also known as “penicillin in cancer.” However, acquired drug resistance limits the clinical use of cisplatin. There are systematic studies on the mechanism of cisplatin resistance, but there is still no effective way to overcome or reverse the drug resistance.