目的探讨神经内镜下经鼻蝶入路垂体瘤切除术的手术技巧及效果。方法 30例经影像学诊断为垂体瘤患者采用内镜下经鼻蝶入路肿瘤切除。结果全切除23例,次全切除6例,部分切除1例。术后临床症状好转27例,术前视力障碍者78.5%获得改善;术前激素水平增高者81.8%有降低。术后主要并发症为尿崩、脑脊液漏等。结论神经内镜下经鼻蝶入路手术具有视野开阔、光线充足等优点,是治疗垂体腺瘤的一种有效方式。 Objective To investigate the surgical technique and effect of endoscopic transnasal pituitary tumor resection by endoscopic nerve endoscopy. Methods Thirty patients with pituitary adenoma diagnosed by imaging were treated with endoscopic transnasal neoplasm resection. Results Total resection in 23 cases, subtotal resection in 6 cases, partial resection in 1 case. Postoperative clinical symptoms improved in 27 cases, 78.5% of preoperative visual impairment were improved; 81.8% of preoperative hormone levels decreased. The main complications of postoperative diabetes insipidus, cerebrospinal fluid leakage. Conclusion Endoscopic transnasal approach has the advantages of wide field of vision and sufficient light, which is an effective way to treat pituitary adenoma.