目的了解2011—2013年南京市溧水区手足口病(HFMD)流行病学特征,为制定防控措施提供依据。方法使用中国疾病预防控制信息系统数据,采用描述流行病学方法对2011—2013年溧水区HFMD发病情况进行分析。结果 2011—2013年溧水区共报告HFMD3 443例,2011年发病率最高(339.41/10万),之后呈下降趋势。重症病例70例,无死亡病例。全年有2个发病高峰,分别为4—7月和11—12月份。各镇均有发病,各镇间发病水平差异明显。男性发病高于女性,男女发病率差异有统计学意义。0~5岁儿童占总病例的95.56%。绝大多数病例为幼托儿童和散居儿童。245例HFMD病例病原检测结果:EV71、Cox A16、其他肠道病毒分别占实验室诊断病例的38.10%、25.17%、36.73%。重症病例以EV71感染为主。结论溧水区手足口病季节、地区、性别、年龄及人群分布特征明显。5岁以下幼托和散居儿童是HFMD防控的重点人群。不同年份优势毒株不同。 Objective To understand the epidemiological characteristics of hand-foot-mouth disease (HFMD) in Lishui District of Nanjing City from 2011 to 2013 and provide the basis for prevention and control measures. Methods The epidemiological method was used to analyze the incidence of HFMD in Lishui District from 2011 to 2013 using the data of China Disease Prevention and Control Information System. Results A total of 443 cases of HFMD3 were reported in Lishui district from 2011 to 2013, with the highest incidence in 2011 (339.41 / 100000) and then a downward trend. 70 cases of severe cases, no deaths. There are 2 peak incidences throughout the year, from April to July and from November to December respectively. The incidence of all towns, the incidence of significant differences between the towns. The incidence of males is higher than that of females, and the difference between males and females is statistically significant. 0 to 5 years old children accounted for 95.56% of the total cases. The vast majority of cases are kindergarten children and diaspora children. The pathogen test results of 245 HFMD cases: EV71, Cox A16 and other enterovirus accounted for 38.10%, 25.17% and 36.73% of the laboratory diagnostic cases respectively. Severe cases of EV71 infection. Conclusion The distribution of hand, foot and mouth disease in Lishui District in season, region, sex, age and population are obvious. Kindergartens and diasporas under the age of 5 are the focus of HFMD prevention and control. Different strains of different strains of different ages.