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目的:为了探究儿童急性上呼吸道感染治疗中抗生素的使用情况,以及相关风险因素和应对策略研究。方法:根据我院儿科2011年10月-2013年10月所收治1128例儿童急性上呼吸到感染患者,随机选取800例处方中含有抗生素类药物的患者资料进行研究。结果:1128例患者中抗生素处方占1066例,抗生素使用率为94.50%;800名患者中,抗生素单独使用512例,占64%,双联用药219例,占27.38%,三联或多联用药69例,占8.63%。按照药物使用频率:美洛西林>青霉素G>舒巴坦>阿奇霉素。不合理处方17单,占2.12%;不良反应发生概率为4.13%,以过敏反应和毒性反应为主,无严重病变者。结论:在儿童急性上呼吸道感染治疗过程中仍然存在抗生素类药物滥用以及处方不合理的情况,合理用药、加强监管、综合分析、优化医资才能从根本上降低该类事件的发生概率。
OBJECTIVE: To investigate the use of antibiotics in the treatment of acute upper respiratory tract infection in children, and to study the related risk factors and coping strategies. Methods: A total of 1128 children with acute upper respiratory tract infection who were admitted to our hospital from October 2011 to October 2013 were selected randomly to study the data of 800 patients with antibiotics. Results: Among the 1128 patients, 1066 were antibiotic prescriptions and the antibiotic use rate was 94.50%. Of the 800 patients, 512 were used alone, accounting for 64% of the 800 patients, 219 were dual therapy (27.38%), and three or more combined drugs For example, accounting for 8.63%. According to the frequency of drug use: mezlocillin> penicillin G> sulbactam> azithromycin. Unreasonable prescription 17 single, accounting for 2.12%; the probability of adverse reactions was 4.13%, mainly allergic reactions and toxic reactions, no serious disease. Conclusion: There are still cases of abuse of antibiotics and unreasonable prescription during the treatment of acute upper respiratory tract infection in children. Rational use of drugs, strengthening of supervision, comprehensive analysis and optimization of medical resources can fundamentally reduce the probability of occurrence of such events.