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目的:了解轮状病毒腹泻患儿心肌酶谱水平的变化规律。方法:选取2006年12月~2009年4月于河南省濮阳市油田总医院进行治疗的89例轮状病毒患儿为观察对象,根据脱水程度分为3组,A组(轻度脱水组)30例、B组(中度脱水组)30例和C组(重度脱水组)29例,同时选取同期的健康幼儿为对照组(D组)30例,对所有患儿的心肌酶谱水平进行检测,并加以研究比较。结果:经研究比较发现,腹泻患儿的ALT、AST、CK、CK-MB、LDH及HBDH水平明显高于健康患儿,同时随着脱水程度的加重,其水平也增高,C组各项检测指标与其他各组比较,均有统计学差异(P<0.05或P<0.01)。结论:关于轮状病毒腹泻幼儿血清心肌酶谱水平的检测研究,为治疗提供有利的依据,值得临床进一步研究及探讨。
Objective: To understand the changes of myocardial enzymes in children with rotavirus diarrhea. Methods: A total of 89 children with rotavirus who were treated in Puyang Oilfield General Hospital from December 2006 to April 2009 were selected and divided into 3 groups according to the degree of dehydration. Group A (mild dehydration group) 30 cases, 30 cases in group B (moderate dehydration group) and 29 cases in group C (severe dehydration group) .30 cases of healthy children in the same period were selected as the control group (group D) Test, and to study and compare. Results: The study found that children with diarrhea ALT, AST, CK, CK-MB, LDH and HBDH levels were significantly higher than healthy children, at the same time with the degree of dehydration, the level also increased, C group of tests The indexes were statistically different from other groups (P <0.05 or P <0.01). Conclusion: The detection of serum myocardial enzymes in children with rotavirus diarrhea provides a good basis for the treatment, which deserves clinical further study and discussion.