论文部分内容阅读
目的 :探讨丝裂霉素C(mitomycinC ,MMC)对泪囊鼻腔吻合术的效果。方法 :将 92例 1 0 5只眼慢性泪囊炎随机分为MMC组 4 8例 55只眼和对照组 4 4例 50只眼 ,MMC组术中应用 0 4mg/mlMMC ,对照组未用MMC ,术后平均随访 2 9个月。结果 :手术成功率 :MMC组为 98 0 8% ,对照组为82 61 % (P <0 0 5)。吻合口开通率 :MMC组为 1 0 0 % ,对照组为 82 61 % (P <0 0 1 )。前后瓣膜愈合时间 :MMC组为 7 86± 2 75天 ,对照组为 7 2 2± 2 2 3天 (P >0 0 5)。吻合口出血发生率 :MMC组为3 62 % ,对照组为 2 %。结论 :MMC可作为治疗慢性泪囊炎的一种安全、简单、有效的辅助药物 ,明显提高手术成功率
Objective: To investigate the effect of mitomycin C (MMC) on dacryocystorhinostomy. Methods: A total of 92 cases (105 eyes) of chronic dacryocystitis were randomly divided into 48 cases (55 eyes) of the MMC group and 44 cases (50 cases) of the control group. The MMC group received 0 4 mg / ml MMC, while the control group did not receive MMC The mean follow-up was 29 months. Results: The success rate of surgery was 98 0 8% in MMC group and 82 61% in control group (P 0 05). Anastomotic opening rate was 100% in the MMC group and 82 61% in the control group (P <0.01). The anteroposterior valve healing time was 7 86 ± 2 75 days in MMC group and 72 22 ± 23 days in control group (P 0 05). The incidence of anastomotic bleeding was 32.6% in the MMC group and 2% in the control group. Conclusion: MMC can be used as a safe, simple and effective adjuvant for the treatment of chronic dacryocystitis and significantly improve the success rate of surgery