论文部分内容阅读
目的探讨按一定时间比例交替进行联机血液透析滤过的前、后稀释对临床肝素用量的影响。方法符合入选标准的慢性肾衰维持性血液透析30例患者,自身对照分组,均进行前、后交替稀释(实验)与后稀释(对照)各3例次HDF治疗;对比两组肝素用量、体外循环管路凝血和透析器复用情况,计算KT/V值,对比两种透析方法的每次透析效率。结果肝素用量实验组比对照组,高凝状态减少了43.02%,而透析器Ⅱ级以上凝血发生率差异有显著性(P<0.05);非高凝状态患者肝素用量减少59.01%,出血素质减少了100%,透析器均为0~I级凝血,(P>0.05)无统计学意义,KT/V值:实验组为±1.383,对照组为±1.32。结论该模式不影响透析效果,又可减少1/2以上的肝素用量,且透析器易清洗。
Objective To investigate the effect of on-line heparin dose by on-line hemodiafiltration before and after dilution in a certain period of time. Methods Thirty patients with chronic renal failure who underwent maintenance hemodialysis were enrolled in this study. All patients were divided into two groups: control group, HDT treatment with three dilutions (control) before and after. Circulation of blood coagulation and dialyzer reuse cases, calculate the KT / V value, comparing the two dialysis methods of each dialysis efficiency. Results Compared with the control group, the amount of heparin in the experimental group decreased by 43.02%, while there was a significant difference in the incidence of coagulation between the dialysate grade Ⅱ and the control group (P <0.05). In the non-hypercoagulable group, the heparin dosage decreased by 59.01% and the hemorrhagic diathesis decreased (P> 0.05). The KT / V values were ± 1.383 in the experimental group and ± 1.32 in the control group. Conclusion This mode does not affect the dialysis effect, but also reduce the amount of heparin more than 1/2, and dialyzer easy to clean.