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目的探讨缩宫素与卡前列素氨丁三醇对足月产妇剖宫产术后出血情况、胃肠功能恢复及首次排尿时间的影响。方法选取该院2014年10月-2016年10月收治的足月产妇共130例为研究对象,按随机数字表法分为对照组(65例)和观察组(65例),分别在剖宫产术后给予缩宫素与卡前列素氨丁三醇;比较两组患者术后2 h和24 h出血量,胃肠功能恢复时间,首次排尿时间及不良反应发生率等。结果观察组患者术后2 h和24 h出血量均显著少于对照组,胃肠功能恢复时间显著短于对照组,差异有统计学意义(t=3.14、3.30、2.74,均P<0.05);观察组患者首次排尿时间显著优于对照组,差异有统计学意义(F=3.78,P<0.05);同时两组患者不良反应发生率比较差异无统计学意义(χ~2=0.97,P>0.05)。结论足月产妇剖宫产术后给予卡前列素氨丁三醇可有效减少术后出血量,促进胃肠功能恢复和早期排尿,且未增加不良反应发生风险,其价值优于缩宫素。
Objective To investigate the effects of oxytocin and carboprost on the bleeding after cesarean section, the recovery of gastrointestinal function and the time of first urination in full-term pregnant women. Methods A total of 130 full-term pregnant women admitted to our hospital from October 2014 to October 2016 were selected as study subjects. They were divided into control group (65 cases) and observation group (65 cases) according to random number table. Oxytocin and carboprost tromethamine were given after operation. The bleeding volume, gastrointestinal function recovery time, the time of first urination and the incidence of adverse reactions were compared between the two groups at 2 h and 24 h after operation. Results The bleeding volume at 2 h and 24 h after operation in observation group was significantly less than that in control group, and the recovery time of gastrointestinal function was significantly shorter than that in control group (t = 3.14, 3.30 and 2.74, both P <0.05) ; The first urination time in the observation group was significantly better than that in the control group, the difference was statistically significant (F = 3.78, P <0.05); while there was no significant difference in the incidence of adverse reactions between the two groups (χ ~ 2 = 0.97, P > 0.05). Conclusion Full-term post-cesarean delivery of carboprost trometamol can effectively reduce postoperative bleeding, promote gastrointestinal function recovery and early urination, and did not increase the risk of adverse reactions, its value is better than oxytocin.