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目的探讨奥扎格雷联合持续泵入普通肝素治疗不同类型脑梗死的近期疗效。方法将106例急性脑梗死患者入院后进行TOAST分型,每型分为治疗组和对照组,治疗组加用奥扎格雷注射液联合普通肝素持续静脉泵入,二组进行总有效率及日常生活活动能力评分对比。结果心源性脑梗死和大动脉粥样硬化性脑梗死治疗组总有效率及日常生活活动能力评分均优于对照组,二组比较差异有统计学意义(P<0.05)。结论奥扎格雷联合持续泵入普通肝素治疗急性脑梗死的方案,应根据TOAST分型中的不用亚型进行个体化,在心源性脑梗死和大动脉粥样硬化性脑梗死二种亚型中疗效确切,值得临床推广。
Objective To investigate the short-term curative effect of ozagrel combined with continuous heparin pump on different types of cerebral infarction. Methods One hundred and sixty patients with acute cerebral infarction were admitted to the hospital for TOAST typing. Each type was divided into treatment group and control group. Ozagrel injection plus UFH was given to the treatment group. The total effective rate and daily routine Life activity ability score comparison. Results The total effective rate and activities of daily living in patients with cardiogenic cerebral infarction and large atherosclerotic cerebral infarction were better than those in control group. There was significant difference between the two groups (P <0.05). Conclusion Ozagrel combined with continuous infusion of unfractionated heparin in the treatment of acute cerebral infarction program should be based on the subtypes of TOAST classification without individualized in both cerebral infarction and cerebral atherosclerotic cerebral infarction in two subtypes Exactly, it is worth clinical promotion.