Roles of Smad3 and Smad7 in rat pancreatic stellate cells activated by transforming growth factor-be

来源 :国际肝胆胰疾病杂志:英文版 | 被引量 : 0次 | 上传用户:liangjingyu1
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
BACKGROUND:Pancreatic stellate cells(PSCs) play a major role in promoting pancreatic fibrosis.Transforming growth factor beta 1(TGF-β1) is a critical mediator of this process.This study aimed to determine the expression of the Smad3 and Smad7 genes in the
其他文献
BACKGROUND: The number of females who undergo liver transplantation is growing and sometimes gynecologic operations are needed to control gynecologic diseases a
BACKGROUND:To physiologically reconstruct the biliary tract,Crema et al suggested the application of the Monti principle to the biliary tract,already used in hu
BACKGROUND:Because of the shortage of deceased donors with livers fit for transplantation,living donor liver transplantation(LDLT)is becoming an attractive alte
BACKGROUND:In the field of gene therapy,viral vectors as delivery tools have a number of disadvantages for medical application.This study aimed to explore a nov
BACKGROUND:There are more than 100 million asymptomatic HBV carriers(ASCs)in China and they are at a high risk of developing liver disease,which creates a serio
BACKGROUND:Gadolinium-enhanced multi-phase dynamic imaging has improved the accuracy of the diagnosis of hypervascular hepatocellular carcinoma (HCC),but using
BACKGROUND:Recent studies have confirmed that the expression of Ezrin,hepatocyte growth factor(HGF)and its receptor(C-met)is related to the genesis,progress,inv
BACKGROUND:Hepatocellular carcinoma(HCC)which is always refractory to most chemotherapeutic agents may result in poor survival of patients with advanced HCC. On
BACKGROUND:In liver transplantation,acute cellular rejection(ACR)is still a major complication that can lead to mortality.Bile secretion has been considered as
BACKGROUND:Alterations in DNA methylation occur during the pathogenesis of human tumors.In this study, we investigated the influence of DNA methyltransferase 3b