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目的 :探讨潘通 (己酮可可碱 )治疗急性缺血性中风的疗效。方法 :潘通与低分子右旋糖酐 +川芎素进行对照研究 ,治疗急性缺血性中风各 3 9例 ,于 14d和 2 1d分别观察疗效。结果 :潘通治疗组血胆固醇、血小板聚集率、纤维蛋白原和全血粘度 (高切 )有显著差异 ,以血浆粘度改变极其显著 (P <0 .0 0 1) ;对照组经统计学处理血小板聚集率、全血粘度 (高切 )和血浆粘度有显著差异 (P <0 .0 2 ) ;两组总有效率分别为 66.67% ,84 .61%和 5 8.97% ,71.79% ,无显著差异。结论 :潘通治疗急性缺血性中风效果明显 ,不良反应轻微 ,可长期用药
Objective: To investigate the efficacy of Pantophen (pentoxifylline) in the treatment of acute ischemic stroke. Methods: Pantophen and low molecular weight dextran + sodium ferulate control study, the treatment of acute ischemic stroke in 39 cases, 14d and 21d were observed. Results: There were significant differences in the serum cholesterol, platelet aggregation rate, fibrinogen and whole blood viscosity (high-cut) in the Pantophenacin treatment group, and the plasma viscosity change was extremely significant (P <0.01). The control group was statistically The platelet aggregation rate, whole blood viscosity (high shear) and plasma viscosity were significantly different (P <0. 02). The total effective rates of the two groups were 66.67%, 84.61% and 59.97%, 71.79% difference. Conclusion: Pantone treatment of acute ischemic stroke effect is obvious, minor adverse reactions, long-term medication