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目的探讨隐性心功能不全合并心电图PTF-V1阳性与血浆BNP关系。方法依据心电图PTFV1分为两组:A组PTFV1>-0.04mms(PTF-V1阴性),B组PTF-V1≤-0.04mms(PTF-V1阳性),每组各120例;两组患者均进行血尿常规、血凝常规、肝肾功能、电解质、血糖、CK-MB、肌钙蛋白、脑钠肽(BNP)、甲状腺功能、心脏彩超[左室舒张末期径(LVDd)、左心室收缩末期径(LVSD)左房内径(LAD)、左室射血分数(LVEF)]、胸片、心电图等检查。所有计量资料以均数±标准差(x±s)表示,组间比较采用成组设计的t检验,以P<0.05为有显著性差异。结果 B组PTFV1≤-0.04mms(PTF-V1阳性)组血浆BNP水平明显高于A组,同时B组左房内径、左室舒张末期径、左室收缩末期径与BNP正相关;与LVEF、E/A负相关。结论心电图PTF-V1阳性患者提示存在隐性心功能不全。
Objective To investigate the relationship between PTF-V1 positive electrocardiogram (ECG) and plasma BNP in patients with implicit cardiac dysfunction. Methods PTFV1 was divided into two groups based on PTFV1: PTFV1> -0.04mms in group A (PTF-V1 negative), PTF-V1≤-0.04mms in group B (PTF-V1 positive) Hematuria Conventional, Hemagglutination, Liver and Kidney Functions, Electrolytes, Blood Glucose, CK-MB, Troponin, BNP, Thyroid Function, Cardiac Color Doppler, Left Ventricular Diastolic Diastasis (LVDd) (LVSD) left atrial diameter (LAD), left ventricular ejection fraction (LVEF)], chest X-ray, ECG and other tests. All measurement data to mean ± standard deviation (x ± s) that the comparison between groups using t-test group design, P <0.05 was significant differences. Results The level of plasma BNP in PTFV1≤-0.04mms (PTF-V1 positive) group was significantly higher than that in group A, while the left atrium diameter, left ventricular end-diastolic diameter and left ventricular end-systolic diameter in group B were positively correlated with BNP; E / A negative correlation. Conclusions Patients with PTF-V1 positive electrocardiogram suggest implicit cardiac dysfunction.