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读了山东医刊64年第8期,吕雁序医师的国产右旋糖酐引起过敏性休克一例后,获益非浅。但本人对该文尚有一些不成熟的看法,愿提出与作者、读者共同讨论。吕医师云:“右旋糖酐极少发生过敏反应国内尚未见有报告”。但据本人手头有限文献资料得知:(一)此种过敏反应初期报告为1.4％;(二)刘慕伟、王培佩二氏,亦已有同样之报告一例。再者据吕文所述,此患者是否有注射右旋糖酐之适应症,也颇值得研究。首先,患者手术后情况良好,既已静脉滴注5％葡萄糖盐水500毫升,似无再用右旋糖酐之必要。此外,右旋糖酐缺乏营养价值,它除能代替血浆以维持渗透压外,很少有其它药理作用。吕文患者“虽然营养状况较差”,注射
After reading the Shandong Medical Journal 64, No. 8, Dr. Lv Yan order physician made dextran an example of anaphylactic shock, benefited greatly. However, I still have some immature opinions on this article and would like to discuss with authors and readers. Dr Lv said: “There have been no reports of allergic reactions in the world. However, according to my limited literature on hand, (1) the initial report of such an allergic reaction was 1.4%; (b) Liu Muwei and Wang Pei Pei, two cases of the same report have also been reported. Furthermore, according to Lv Wen said, whether this patient has dextran injection indications, is also worth studying. First of all, the patient is in good condition after surgery, already with intravenous infusion of 500 ml of 5% dextrose in saline and no need for reuse of dextran. In addition, dextran lacks nutritional value, and it has few other pharmacological effects except that it can replace the plasma to maintain the osmotic pressure. Lu Wen patients, ”although poor nutritional status," injection