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前列腺素E_2(PGE_2)具有广泛的生物学效应,在人体各个组织中发挥极为重要的调节作用。多种疾病的产生都与PGE_2失调有关。在临床应用上,对控制生育和治疗消化道溃疡、新生儿重症先天性心脏病等方面已有肯定评价。在治疗动脉粥样硬化、肝病及器官移植的应用上,存在开发潜力。
Prostaglandin E 2 (PGE 2) has a wide range of biological effects and plays an extremely important regulatory role in various tissues of the human body. A variety of diseases are associated with dysregulation of PGE2. In clinical application, control of reproductive and treatment of peptic ulcer, neonatal severe congenital heart disease and other aspects have been affirmed. In the treatment of atherosclerosis, liver disease and organ transplantation applications, there is development potential.