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本文用碱性和酸性磷酸酶、5′-核苷酸酶、非特异性酯酶和琥珀酸脱氢酶的组织化学方法观察了10例人体肝细胞癌和癌周肝组织的变化。一般来说,肝细胞上述酶的活性明显减弱至消失,仅见一例碱性磷酸酶和另一例酸性磷酸酶呈现明显活性。而癌周肝组织无论是肝硬化或肝纤维化均显示正常肝细胞的酶活性。癌和癌周肝具有明显的酶的差异性。
In this paper, the histochemical methods of alkaline and acid phosphatase, 5′-nucleotidase, non-specific esterase and succinate dehydrogenase were used to observe the changes of human hepatocellular carcinoma and hepatic tissue in 10 cases. In general, the activities of the aforementioned enzymes in hepatocytes were significantly reduced to disappear, and only one case of alkaline phosphatase and another case of acid phosphatase showed significant activity. On the other hand, hepatic tissue in the liver cancer showed normal hepatocyte enzymatic activity in both liver cirrhosis and hepatic fibrosis. Carcinoma and cancerous liver have obvious enzyme differences.