患者,女,43岁。主因间断贫血、出血15年,咳嗽、咳痰5个月,加重伴发热1周,于2006年12月第4次入院。否认传染病、过敏、感染、特殊用药及结缔组织病史。体检:体温37.2℃,重度贫血貌,全身浅表淋巴结无肿大,全身皮肤遍布扁平疣,其表面有色素沉着,以四肢为重,巩膜轻度黄染,咽无充血, Patient, female, 43 years old. The main cause of intermittent anemia, bleeding for 15 years, cough, sputum for 5 months, increased fever with 1 week, in December 2006 the 4th admission. Deny infectious diseases, allergies, infections, special medication and connective tissue history. Physical examination: body temperature 37.2 ℃, severe anemia appearance, systemic superficial lymph nodes without swelling, the body skin covered with flat warts, the surface of pigmentation, to the limbs, scleral mild yellow dye, pharynx without congestion,