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Alexander 病(AD)是一种进行性神经系变性病,以往生前诊断均靠脑活检。作者报导1例用 CT 作出诊断的患者如下:女婴,头胎,其父健康,母有癫痫,长期服用大仑丁和鲁米那,于妊娠43周剖腹产娩出,时体重3.2Kg,无窒息。4周时有倦睡,易激惹,体重减轻.9周时吸吮无力,伴呕吐而入院。时体重3.65Kg,身长与头围均低于正常值。神清,竖头困难,全身肌张力增强。11周时作 CT 见两侧脑室轻—中度扩大,对比增强见两侧脑室额角周围白质、尾状核及丘脑密度增加.4月时头围迅速增大而作脑室—腹腔引流术。此后又发生部份性癫痫发作,7月时
Alexander’s disease (AD) is a progressive neurodegenerative disease that relies on brain biopsies for past diagnoses. The authors report that 1 patient diagnosed with CT was as follows: baby girl, first child, healthy father, mother with epilepsy, long-term use of Dalunding and luminal, delivered at caesarean section at 43 weeks gestation, with a body weight of 3.2 kg and no asphyxia . Sleepy 4 weeks, irritability, weight loss .9 weeks sucking weakness, with vomiting and admission. Body weight 3.65Kg, length and head circumference are lower than normal. Clear, vertical head difficulties, increased body muscle tone. At week 11, CT showed mild to moderate ventricles enlargement on both sides, with contrast enhancement of white matter, caudate nucleus and thalamic density around the forehead on both sides of the brain.24 The head circumference rapidly increased for intraventricular-abdominal drainage in April. Subsequent seizures occurred again in July