论文部分内容阅读
目的慢性肺源性心脏病(简称慢性肺心病)是临床常见病,常伴有循环系统症状,在首诊与急诊中影响医师对本病分期与严重程度的诊断与鉴别,因此寻求一种相对简便快捷的鉴别方法有着重要的临床意义。方法将90例慢性肺源性心脏病患者分为肺心功能代偿期、肺心功能失代偿之呼吸困难期与肺心功能失代偿之右心衰竭期等三期,每期30例;被研究者在入组后第2天检测血浆脑钠肽(BNP)与彩色二维超声,分析临床检测结果与疾病严重程度的关系。结果肺心功能代偿期、肺心功能失代偿之呼吸困难期与肺心功能失代偿之右心衰竭期血浆BNP依次为(81±47)ng/L、(138±56)ng/L、(214±84)ng/L,随着症状的加重BNP指数呈现升高的趋势。结论血浆BNP水平可作为评估慢性肺心病患者临床症状及右心室功能不全严重程度的指标,也可做为评价疗效和判定肺心病预后的重要参考指标。
Objective Chronic cor pulmonale (referred to as chronic cor pulmonale) is a common clinical disease, often accompanied by symptoms of circulatory system, affecting physicians in the first diagnosis and emergency diagnosis and identification of the disease stage and severity, so to seek a relative Simple and quick identification method has important clinical significance. Methods Ninety patients with chronic cor pulmonale were divided into three phases: pulmonary heart decompensation, dyspnoea of decompensation of pulmonary heart and right heart failure of decompensated pulmonary heart function. Each period included 30 cases The subjects were tested for plasma brain natriuretic peptide (BNP) and colorimetric ultrasound on the second day after enrollment. The relationship between the clinical test results and the severity of the disease was analyzed. Results Plasma BNP levels in right heart failure patients with dyspnoea and decompensated pulmonary heart disease were (81 ± 47) ng / L, (138 ± 56) ng / L, (214 ± 84) ng / L, with the worsening of BNP index showed an upward trend. Conclusion Plasma BNP level can be used as an index to evaluate the clinical symptoms and the severity of right ventricular dysfunction in patients with chronic cor pulmonale. It can also be used as an important reference index to evaluate the curative effect and prognosis of pulmonary heart disease.