细胞因子(CK)是由多种细胞产生的具有多种生物活性的蛋白质或肽类,通过与相应靶细胞上的细胞因子受体结合而产生免疫调节作用和某些效应功能。根据其生物效应特点目前分为白介素(IL)、干扰素(IFN)、肿瘤坏死因子(TNF)、转化生长因子(TGF)等几大类。自身免疫性甲状腺疾病(AITD)包括Graves病(GD)和桥本甲状腺炎(HT),主要与甲状腺上皮细胞 Cytokines (CKs) are proteins or peptides produced by a variety of cells with a variety of biological activities that produce immunomodulatory effects and certain effector functions by binding to the cytokine receptors on the corresponding target cells. According to the characteristics of its biological effects are divided into several major categories of interleukin (IL), interferon (IFN), tumor necrosis factor (TNF), transforming growth factor (TGF) and so on. Autoimmune thyroid disease (AITD) includes Graves disease (GD) and Hashimoto’s thyroiditis (HT), mainly with thyroid epithelial cells