论文部分内容阅读
目的优化淫羊藿配方颗粒的提取工艺。方法采用单因素试验结合Box-Behnken效应面分析法,以出膏率、淫羊藿苷含量为评价指标,考察提取时间、加水量、提取次数等因素对提取工艺的影响。结果优选提取工艺为:22倍量水,煎煮提取2次,每次36 min,淫羊藿苷含量可达10.16 mg.g-1,出膏率为17.26%。结论 Box-Be-hnken试验设计法用于淫羊藿配方颗粒提取工艺的优选是可行的,数学模型的预测值与试验观察值相符。
Objective To optimize the extraction process of Epimedium formula granules. Methods The single factor test combined with Box-Behnken effect surface analysis method, with the ointment rate, icariin content as the evaluation index, to investigate the extraction time, water, extraction times and other factors on the extraction process. Results The optimum extraction process was as follows: 22 times the amount of water, boiling extraction twice, 36 min each time, icariin content of up to 10.16 mg.g-1, the rate of 17.26% cream. Conclusion Box-Be-hnken experimental design method for the extraction process of Epimedium prescription particles is feasible, the predictive value of the mathematical model is consistent with the experimental observations.