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近年来肝脏病的研究有了显著的进步,但未解决的问题也很多。本文参照“Liver”、“Seminars in Liver Diseases”、“The Liver Annual”等杂志,试将近1~2年的研究成果,介绍如下。一、非甲非乙型肝炎在病毒性肝炎中,对非甲非乙型(NANB)肝炎的研究正在进行,最大的问题就是抗原抗体系久未搞清。继东北大白地等报告C抗原之后,Trepo、Suh、藤松等报告了琼脂凝胶内沉降反应等各种方法。但由于抗原价低、免疫复合物的形成、抗原不稳定、反应抗体量少等原因,至今尚未找到大家所共认的抗原抗体系。Dienstag等用Raji细胞的放射免疫分析法,对急性NANB肝炎检出率为50%,慢性NANB肝炎为70%。
In recent years, the study of liver disease has made significant progress, but there are also many unsolved problems. This article refers to “Liver”, “Seminars in Liver Diseases”, “The Liver Annual” and other magazines, try nearly 1 to 2 years of research results are described below. First, non-A non-hepatitis B In viral hepatitis, the study of non-A non-B type (NANB) hepatitis is ongoing, the biggest problem is the antigen-antibody system has not been identified. Following reports of C antigen from Tohoku Daiba et al., Trepo, Suh and Fujisugi reported various methods such as sedimentation reaction in agar gel. However, due to low antigen prices, the formation of immune complexes, antigen instability, the amount of reactive antibodies and other reasons, so far we have not yet found all the anti-antigen system. Radionuclideanalysis by Raji cells by Dienstag et al. Showed a 50% detection rate of acute NANB hepatitis and 70% of chronic NANB hepatitis.