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1981年以前我院对破伤风的治疗,多采用氯丙嗪等镇静药物控制抽搐,结果并发症多,死亡率高。1981年以后全部改用大剂量安定治疗,效果较满意,现报告如下: 临床资料:本组40例,男23例,女17例。年龄3 1/2～60岁;全部病例都没有接受过破伤风抗毒素预防注射。TAT用量:5～20万iu肌注或静滴。安定用量:轻型:1.0～2.0mg/kg/d,分4～6次肌注,或缓慢静滴,可连用3～5天。中型:3～6mg/kg/d缓慢静滴,连用6～8天,逐
Before 1981 in our hospital for the treatment of tetanus, and more use of sedatives such as chlorpromazine to control seizures, the results of complications and high mortality. After 1981, all the switch to high-dose stability treatment, the effect is more satisfactory, are as follows: Clinical data: The group of 40 patients, 23 males and 17 females. Age 3 1/2 ~ 60 years old; all cases have not received tetanus antitoxin injection. TAT dosage: 5 ~ 200,000 iu intramuscular or intravenous infusion. Consumption: light: 1.0 ~ 2.0mg / kg / d, divided into 4 to 6 times intramuscularly, or intravenous infusion, can be used in conjunction 3 to 5 days. Medium: 3 ~ 6mg / kg / d slow intravenous infusion, once every 6 to 8 days, by