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目的 :探讨用门控心血池显像在诊断各期高血压的左室功能改变的意义。方法 :选取门控心血池检查且临床资料齐全者共 10 0例 ,其中一期 2 0例 ,二期 37例 ,三期 43例。正常对照组 5 0例。用SPOPHY DS7型 SPECT,配低能平行孔通用准直器 ,常规9m Tc- Rbc体内标记法。由 ECG R波触发门电路 ,行左室门控核素心血池显像 ,每一 R- R间期采集 16帧 ,约 40 0～ 6 0 0个心动周期。用 FRANKFURT门处理程序 ,自动产生各自时相图、时相直方图及振幅图和下列指标 :左室整体射血分数 GEF(% ) ,左室舒张末期容积 EDV(ml) ,收缩前期时间 PEP(ms) ,高峰射血时间 TPE(ms) ,舒张末到收缩末时间 ES(ms) ,高峰充盈时间 TPF(ms) ,快速充盈时间 RFT(ms) ,高峰射血率PER(l/ s) ,高峰充盈率 PFR(l/ s)及心室相角程 PS(度 )等。结果 :高血压病各期心功能参数与正常组比较均有明显差异 ,但各期之间除 EDV在高血压病三期明显增大外 ,其它各指标未见差别 ;时间参数比较 ,PEP、TPE、TPF在高血压病三期明显延长。心功能于 3～ 4级时 ,各项参数较 1级者明显为差。相关分析表明高血压病的分期与 EDV和年龄相关 (r>=0 .2 6 ,P<0 .0 1) ,但不如临床心功能分级关系密切 (r=0 .5 5 ) ;PFR、GEF、PER与高血压病的分期无明显相关但与心功能分级有
Objective: To explore the significance of using gated blood pool imaging in the diagnosis of left ventricular dysfunction in all stages of hypertension. Methods: A total of 100 cases with complete glandular blood pool examination were selected, including 20 cases of stage I, 37 cases of stage II and 43 cases of stage III. Normal control group 50 cases. With SPOPHY DS7 SPECT, with low parallel collimator universal collimator, conventional 9m Tc-Rbc in vivo labeling method. Triggered by the ECG R wave gate, left ventricular gated cardiac pool imaging, each R-R interval acquisition of 16 frames, about 40 0 ~ 600 cardiac cycles. With FRANKFURT door processing program, automatically generate their own phase diagram, time histogram and amplitude and the following indicators: left ventricular ejection fraction GEF (%), left ventricular end-diastolic volume EDV (ml), pre-contraction time PEP ( (ms), peak ejection time TPE (ms), end diastolic to end time ES (ms), peak filling time TPF (ms), rapid filling time RFT (ms), peak ejection rate PER Peak Filling Rate PFR (l / s) and ventricular phase angle of PS (degrees) and so on. Results: There were significant differences in cardiac function parameters between hypertensive patients and normal subjects at each stage. However, there was no significant difference between the two groups except for EDV in the third stage of hypertensive disease. Compared with the time parameters, PEP, TPE, TPF significantly prolonged in the third phase of hypertension. Heart function at 3 to 4, the parameters were significantly worse than 1. Correlation analysis showed that the stage of hypertension was related to EDV and age (r> = 0.26, P <0.01), but not as good as the classification of clinical cardiac function (r = 0.55); PFR, GEF , PER and stage of hypertension no significant correlation but with the classification of cardiac function