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由于乙型肝炎病毒 (ＨＢＶ)宿主范围狭小 ,主要对人类和黑猩猩易感 ,因而为抗ＨＢＶ药物筛选的研究带来了很大的困难。本文探索建立了一种利用乙型肝炎病人外周血单个核细胞 (ＰＢＭＣ)进行体外培养来筛选抗ＨＢＶ药物的新系统 ,取得了一定的效果。1 资料和方法病例 :选自 199
Due to the narrow host range of Hepatitis B virus (HBV), which is predominantly susceptible to humans and chimpanzees, great difficulties have been encountered in screening anti-HBV drugs. This paper explored the establishment of a new system of screening anti-HBV drugs by in vitro culture of peripheral blood mononuclear cells (PBMCs) from patients with hepatitis B, and achieved some results. 1 Materials and Methods Case: From 199