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临床观察结果证明,砷剂在治疗急性早幼粒细胞白血病(APL)过程中显示出卓越的疗效。复方柏子仁中的雄黄(As_4S_4)可诱导 NB_4、HL-60、K 562白血病细胞株凋亡,柏子仁与雄黄伍用可显著增强其诱导白血病细胞的凋亡,在治疗急性早幼粒
Clinical observations have shown that arsenic agents show excellent efficacy in the treatment of acute promyelocytic leukemia (APL). Realgar (As_4S_4) in Bupleurum nigra can induce the apoptosis of NB_4, HL-60 and K 562 leukemia cell lines. The effects of BCD and DLR on the apoptosis of leukemia cells are significant. In the treatment of acute promyelocytic