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目的探讨丙型肝炎肝硬化与肝源性糖尿病的关系和临床特点。方法对丙型肝炎肝硬化合并肝源性糖尿病79例患者的临床资料进行回顾性分析,并与同期住院的75例无肝源性糖尿病的丙型肝炎肝硬化病例进行对照。结果肝硬化并发肝源性糖尿病的主要临床表现为肝病的症状,糖尿病的“三多一少”症状较少出现,肝源性糖尿病的发生率与肝硬化的严重程度成正相关,肝性脑病、各种感染等并发症的发生率与对照组比较,有统计学意义(P<0.05)。结论肝源性糖尿病也是丙肝肝硬化常见的并发症,应予以积极的护肝治疗、控制血糖和肝硬化并发症。
Objective To investigate the relationship between hepatitis C cirrhosis and liver-derived diabetes mellitus and its clinical features. Methods The clinical data of 79 patients with hepatitis C cirrhosis and liver-derived diabetes mellitus were retrospectively analyzed and compared with 75 hospitalized patients with hepatitis C cirrhosis without liver-derived diabetes during the same period. Results The main clinical manifestations of liver cirrhosis complicated with liver-derived diabetes mellitus were the symptoms of liver disease. The symptoms of diabetes mellitus were less frequent. The incidence of liver-derived diabetes mellitus was positively correlated with the severity of liver cirrhosis. Encephalopathy, various infections and other complications compared with the control group, there was a statistically significant (P <0.05). Conclusion Hepatic-derived diabetes mellitus is also a common complication of hepatitis C cirrhosis and should be treated with active hepatoprotective therapy to control the complications of blood glucose and cirrhosis.