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目的探讨蓝光照射联合茵栀黄治疗新生儿高胆红素血症的临床疗效。方法选取崇左市龙州县人民医院2014年7月—2016年7月收治的高胆红素血症患儿123例,按照治疗方法不同将患儿分为观察组60例与对照组63例。观察组予以茵栀黄口服液+蓝光照射治疗;对照组予以蓝光照射治疗。比较两组患儿临床疗效、血清胆红素水平与症状持续时间。结果观察组患儿临床疗效优于对照组(P<0.05)。治疗前两组患儿血清胆红素水平比较,差异无统计学意义(P>0.05);治疗24、48 h后观察组患儿血清胆红素水平低于对照组(P<0.05);观察组患儿症状持续时间短于对照组(P<0.05)。结论蓝光照射联合茵栀黄治疗新生儿高胆红素血症的临床疗效确切,可有效降低患儿血清总胆红素水平,缩短患儿症状持续时间。
Objective To investigate the clinical effects of blue light irradiation combined with Yinzhihuang on neonatal hyperbilirubinemia. Methods A total of 123 children with hyperbilirubinemia admitted to Longzhou County People’s Hospital of Chongzuo City from July 2014 to July 2016 were divided into observation group (60 cases) and control group (63 cases) . The observation group was treated with Yinzhihuang oral solution + blue light and the control group with blue light irradiation. The clinical efficacy, serum bilirubin level and symptom duration in both groups were compared. Results The clinical efficacy of observation group was better than that of control group (P <0.05). The levels of serum bilirubin in the two groups before treatment were not significantly different (P> 0.05). The level of serum bilirubin in the observation group was lower than that of the control group 24 and 48 hours after treatment (P <0.05) The duration of symptoms in children was shorter than that in control group (P <0.05). Conclusion Blue light irradiation combined with Yinzhihuang neonatal hyperbilirubinemia clinical efficacy is exact, can effectively reduce the serum total bilirubin levels, shorten the duration of symptoms in children.