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目的:分析环磷腺苷葡胺与参麦注射液治疗小儿病毒性心肌炎的临床疗效方法:选取2012年11月至2014年12月该院收治的60例小儿病毒性心肌炎患儿作为观察对象,随机将其分成两组,每组30例。对照组采取常规治疗,实验组在对照组的基础上采取环磷腺苷葡胺与参麦注射液进行治疗,观察比较两组患儿的临床疗效及血浆BNP和CRP水平变化情况。结果:对照组的总有效率(70.00%)显著低于实验组的总有效率(90.00%);两组小儿病毒性心肌炎患儿治疗后的血浆BNP和CRP水平变化情况的比较结果存在显著差异(P<0.05)。结论:对小儿病毒性心肌炎患儿采取环磷腺苷葡胺与参麦注射液联合进行治疗,能够有效降低患儿血浆中的BNP和CRP水平,效果显著。
OBJECTIVE: To analyze the clinical curative effect of cyclophosphamide and shenmai injection on viral myocarditis in children Methods: Sixty children with viral myocarditis admitted in our hospital from November 2012 to December 2014 were selected as the observation objects, Randomly divided into two groups, each group of 30 cases. The control group was treated routinely. The experimental group was treated with amifostine and shenmai injection on the basis of the control group. The clinical efficacy and changes of plasma BNP and CRP levels in both groups were observed and compared. Results: The total effective rate (70.00%) in the control group was significantly lower than that in the experimental group (90.00%). There was significant difference between the two groups in the changes of plasma BNP and CRP levels in children with viral myocarditis (P <0.05). Conclusion: In children with viral myocarditis with cyclophosphamide meglumine and Shenmai injection combined treatment, can effectively reduce the plasma BNP and CRP levels in children, the effect is significant.