目的:Ⅱ型糖尿病异常肌电图与胰岛素、C肽分泌及其尿微量白蛋白的相关研究。方法:回顾性分析2004年1～12月肌电图异常的Ⅱ型糖尿病患者258例的病史资料。结果:各组患者胰岛分泌功能降低,经病程校正后,下肢神经受累和感觉神经受累者胰岛功能更差。24h尿微量白蛋白浓度各组间无显著差异。结论:B细胞功能减退与糖尿病性周围神经病变有关,对下肢神经和感觉神经损害更显著。 OBJECTIVE: To study the relationship between abnormal EMG and insulin, C peptide secretion and urinary microalbuminuria in type 2 diabetes mellitus. Methods: The clinical data of 258 patients with type 2 diabetes mellitus who had EMG abnormalities from January to December in 2004 were analyzed retrospectively. Results: The secretion of pancreatic islets decreased in all groups. After the course of disease was corrected, the islet function of lower extremity nerve involvement and sensory nerve involvement were worse. 24h urinary albumin concentration no significant difference between the groups. CONCLUSION: B-cell dysfunction is associated with diabetic peripheral neuropathy, with more pronounced damage to lower extremity nerves and sensory nerves.