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目的观察沙美特罗替卡松粉吸入剂在尘肺病治疗的效果。方法采用随机对照方法,治疗组在综合治疗基础上加用沙美特罗替卡松粉吸入剂50μg/250μg(沙美特罗/丙酸氟替松)1喷,每天2次;对照组只用综合治疗法。结果治疗后治疗组咳嗽、憋喘和肺内口罗音总有效率分别为71.05%、72.22%和57.14%,均高于对照组的28.57%,21.88%和25.00%。治疗组肺功能各项指标治疗后明显好转,与治疗前比,差异有统计学意义。结论沙美特罗替卡松粉吸入剂在改善患者临床症状和肺功能方面均明显优于对照组,对尘肺病有良好的辅助治疗作用。
Objective To observe the effect of salmeterol and fluticasone powder inhalers in the treatment of pneumoconiosis. Methods A randomized controlled trial was conducted in which the treatment group was treated with salmeterol and fluticasone powder inhalation 50μg / 250μg (salmeterol / fluticasone propionate) 1 spray twice a day on the basis of comprehensive treatment. The control group Treatment. Results After treatment, the total effective rate of cough, wheezing and oral rales in the treatment group were 71.05%, 72.22% and 57.14%, respectively, which were higher than that of the control group by 28.57%, 21.88% and 25.00%, respectively. After treatment, the indexes of pulmonary function in the treatment group were significantly improved compared with before treatment, the difference was statistically significant. Conclusions Salmeterol and fluticasone powder inhalers are better than the control group in improving the clinical symptoms and pulmonary function of patients, and have a good adjuvant therapy for pneumoconiosis.