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目的探讨综合治疗加用大剂量氨溴索对新生儿呼吸窘迫综合征的疗效。方法选择2013年4月至2015年4月呼吸窘迫新生儿120例,根据治疗方法分为两组,每组60例,对照组仅实施综合治疗,试验组给予综合治疗加用大剂量氨溴索,对比两组患儿治疗后的疗效与动脉血氧分压(Pa O2)水平。结果试验组治疗12 h后的总有效率(98.33%)明显高于对照组(58.33%);试验组治疗12 h后的Pa O2水平(77.6±4.0)mm Hg(1 mm Hg=0.133 k Pa)与48 h后的(92.5±4.7)mm Hg均明显优于对照组,差异有统计学意义(P<0.05)。结论综合治疗加用大剂量氨溴索对新生儿呼吸窘迫综合征疗效明显。
Objective To investigate the curative effect of comprehensive treatment combined with high-dose ambroxol on neonatal respiratory distress syndrome. Methods 120 cases of neonatal respiratory distress from April 2013 to April 2015 were divided into two groups according to the treatment method, 60 cases in each group. The control group was only treated with combination therapy. The treatment group was given combined treatment with high-dose ambroxol The curative effect and arterial oxygen tension (Pa O2) level were compared between the two groups. Results The total effective rate (98.33%) in the experimental group after 12 hours of treatment was significantly higher than that in the control group (58.33%). The Pa O2 level in the experimental group after 12 hours of treatment was 77.6 ± 4.0 mm Hg (1 mm Hg = 0.133 kPa ) And 48 h (92.5 ± 4.7) mm Hg were significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Combined treatment with high-dose ambroxol has a significant effect on neonatal respiratory distress syndrome.