In order to minimize the transmitted power in the multi-user orthogonal frequency division multiplexing(OFDM) system, a scheme combining the improved particle swarm optimization(POS) algorithm with genetic algorithm(GA) is proposed to optimize the sub-carriers and bits allocation. In the algorithm, a random velocity between the maximum and minimum particle velocity is used as the updating velocity instead of maximum or minimum velocity when the updated particle velocity is higher than the maximum particle velocity or lower than the minimum particle velocity. Then, the convergence population is used as the initial population of the genetic algorithm to optimize the subcarriers and bits allocation further. Simulation results show that the transmitted power of the proposed algorithm is about 2 d B to 10 d B lower than that of the genetic algorithm, particle swarm optimization algorithm, and Zhang’s algorithm. In order to minimize the transmitted power in the multi-user orthogonal frequency division multiplexing (OFDM) system, a scheme combining the improved particle swarm optimization (POS) algorithm with genetic algorithm (GA) is proposed to optimize the sub-carriers and bits allocation In the algorithm, a random velocity between the maximum and minimum particle velocity is used as the updating particle instead of maximum or minimum velocity when the updated particle velocity is higher than the maximum particle velocity or lower than the minimum particle velocity. Then, the convergence population is used as the initial population of the genetic algorithm to optimize the subcarriers and bits allocation further. Simulation results show that the transmitted power of the proposed algorithm is about 2 d B to 10 d B lower than that of the genetic algorithm, particle swarm optimization algorithm, and Zhang’s algorithm.