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目的研究他汀类药物在治疗2型糖尿病患者高脂血症的疗效和成本,找出一种费用较低、效果显著的治疗方案。方法将收治的168例2型糖尿病高脂血症患者随机分为为A(氟伐他汀)、B(洛伐他汀)、C(普伐他汀)、D(辛伐他汀)4组,比较各组疗效,并进行成本-效果分析。结果A、B、C、D组疗效分别为85.71%、88.10%、83.33%、90.48%(P>0.05),成本-效果比分别为166.58、95.77、163.16、84.90。结论辛伐他汀具有最低的单位效果成本,值得临床上应用。
Objective To study the efficacy and cost of statins in the treatment of type 2 diabetes with hyperlipidemia and to find out a less expensive and effective treatment plan. Methods 168 patients with type 2 diabetes mellitus were randomly divided into four groups: A (fluvastatin), B (lovastatin), C (pravastatin) and D (simvastatin) Group efficacy, and cost-effectiveness analysis. Results The curative effects of group A, B, C and D were 85.71%, 88.10%, 83.33% and 90.48%, respectively. The cost-effectiveness ratios were 166.58, 95.77, 163.16 and 84.90, respectively. Conclusion Simvastatin has the lowest unit cost of effect, which is worth clinical application.