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对141例≥37周的孕妇行阴道后穹隆放置米索前列醇引产。分成3组,剂量分别为100、75和50μg。结果:3组宫颈评分≥5分者,引产1次成功率分别为81.25％、80.95％和80.72％,3组间比较无显著性差异(P>0.05)。最后1次放药至临产开始和总产程时间,3组之间差异有显著性(P<0.01)。3组问急产、产后大出血、羊水粪染的发生率以及新生儿出生评分均有显著性差异(P<0.05)。提示:米索前列醇用于足月妊娠引产,每次于阴道后穹隆放置50～75μg,是一安全有效的引产方法。
141 cases of ≥37 weeks of pregnant women were placed vaginal fornix misoprostol induction of labor. Divided into three groups, the doses were 100,75 and 50μg. Results: The success rates of 1 group with cervical score≥5 and 3 were 81.25%, 80.95% and 80.72%, respectively. There was no significant difference between the three groups (P> 0.05). The last drug release to the beginning of labor and total labor duration, the difference between the three groups was significant (P <0.01). There were significant differences in the incidence of acute and postpartum hemorrhage, meconium-stained amniotic fluid, and neonatal birth scores (P <0.05). Tip: misoprostol for term pregnancy induced labor, each vaginal fornix placed 50 ~ 75μg, is a safe and effective induction of labor.