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目的 了解女性生殖道支原体感染及临床药敏情况。方法 2002年 7月至 2003年 7月浙江绍兴文理学院医学院附属医院对 768例妇科门诊患者进行了宫颈分泌物支原体培养,并对阳性标本做 12种抗生素药敏试验。采用支原体培养、鉴定、药敏一体化试剂盒进行检测。结果 768例中支原体阳性为 433例,感染率为56.4%,其中解脲支原体(UU)、人型支原体(MH)及混合感染的阳性率分别占 51 0% (221例 )、10 9% (47例 )、38.1% (165例)。药物敏感情况:UU单一感染最高为克拉霉素 ( 86.0% ),MH单一感染最高为美满霉素(76.6% ),混合感染为美满霉素 56.95%。结论 在本研究中女性生殖道支原体感染率为 56.4%,克拉霉素是治疗UU感染的首选药,美满霉素是治疗MH和混合感染的首选药。
Objective To understand the female genital Mycoplasma infection and clinical susceptibility. Methods From July 2002 to July 2003, 768 cases of gynecological outpatients underwent mycoplasma culture of cervical secretions from the Affiliated Hospital of Medical College of Shaoxing University of Arts and Sciences, Zhejiang Province. Twelve antibiotic susceptibility tests were performed on positive specimens. Mycoplasma culture, identification, drug sensitivity integration kit for testing. Results The positive rate of mycoplasma in 768 cases was 433 and the infection rate was 56.4%. The positive rates of UU, MH and mixed infection were 51 0% (221 cases) and 109% (9 cases) 47 cases), 38.1% (165 cases). Drug sensitivity: The highest single infection of UU was clarithromycin (86.0%), the highest single infection of MH was minocycline (76.6%), and the mixed infection was minocycline 56.95%. Conclusions In our study, the prevalence of mycoplasma in the female genital tract was 56.4%. Clarithromycin was the first choice for the treatment of UU infection. Minocycline was the first choice for the treatment of MH and mixed infections.