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目的观察血浆脑利钠肽(BNP)在2型糖尿病血管病变时的变化及临床意义。方法选取正常对照组40例,2型糖尿病无血管病变组38例及2型糖尿病血管病变组44例。测定血浆BNP的水平变化。结果 2型糖尿病血管病变组血浆BNP的水平明显高于另外两组(P<0.01)。结论血浆BNP的检测可作为简便,价廉,可靠的糖尿病血管病变的筛选指标。
Objective To observe the changes and clinical significance of plasma brain natriuretic peptide (BNP) in type 2 diabetic patients with vascular disease. Methods Forty cases of normal control group, 38 cases of type 2 diabetes without vascular disease group and 44 cases of type 2 diabetic vascular disease group were selected. Plasma levels of BNP were measured. Results The plasma levels of BNP in type 2 diabetes mellitus were significantly higher than those in the other two groups (P <0.01). Conclusion The detection of plasma BNP can be used as a simple, inexpensive and reliable marker of diabetic vascular disease.