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所谓老化是“长年岁的现象”,即在年龄增长之中,为继成长期,成熟期后第三个退缩期一有特征的变化。年龄增长是一个极为连续的现象,而机体内的变化则是慢慢积累的。关于年龄增长的问题是从不同的角度进行研究的,大体分为分子生物学的,细胞学的,遗传学的,免疫学的,内分泌学的,放射生物学的途径。另外还研究了细胞,组织,脏器,个体等不同水平上的老化。但是不言而喻细胞的老化迟早同脏器的机能减低相联系。关于分子水平上的老化现象。有著名的Hayflick实验。即将人肺成纤维细胞在试管内进行传代培养,约经过6个月(第2相期)细胞增殖虽在进行,但某些细胞发生变异向异质的
The so-called aging is “the phenomenon of long years of age,” that is, in the growth of age, following the growth phase, maturity after the third withdrawal of a characteristic change. Age is a very continuous phenomenon, while changes in the body is slowly accumulated. The issue of age growth is studied from different perspectives and is broadly divided into molecular biology, cytology, genetics, immunology, endocrinology and radiobiology. In addition, cells, tissues, organs, and individuals are studied at different levels of aging. However, it goes without saying that the aging of the cells is linked to a decrease in the functioning of the organ. On the molecular level of aging phenomenon. The famous Hayflick experiment. About human lung fibroblasts subcultured in vitro, after about 6 months (Phase 2) cell proliferation is in progress, but some of the cells mutate to heterogeneous