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来自美国费城的一个研究小组向美国心脏病学院报告说,急性心肌梗塞(MI)发生1小时后应用肝素治疗的初步研究表明,该组78％的患者冠脉重新畅通,无一例发生出血性并发症。 宾夕法尼亚州立大学的内科教授Meister说,有急性MI的心电图改变和临床体征的患者23例,在发病1小时后接受大剂量肝素7500～10000单位静脉推注,18例疼痛迅速缓解,升高的ST段降低2mm以上。静脉推注肝素后,继续滴注肝素800～1000单位/小时,使部分凝血激酶时间保持于正常的2～3倍。
A team from Philadelphia, USA, reported to the American College of Cardiology that a preliminary study of heparin treatment 1 hour after the onset of acute myocardial infarction (MI) showed that in 78% of patients in this group, the coronary circulation was unobstructed and no hemorrhagic event occurred disease. According to Meister, a professor of internal medicine at Pennsylvania State University, 23 patients with acute myocardial infarction and clinical signs of electrocardiographic changes and signs of MI received intravenous bolus injection of 7500 to 10,000 doses of high-dose heparin one hour after onset, and 18 had rapid pain relief and increased ST Segment lower than 2mm. After intravenous injection of heparin, continue to drip heparin 800 ~ 1000 units / hour, so that part of the thromboplastin time to maintain normal 2 to 3 times.