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用放射免疫分析方法（RIA）测定60例糖尿病早期肾病患者晨尿中上皮细胞生长因子（hEGF）的浓度和其中的21例经治疗后好转的患者晨尿中hEGF浓度，结果显示糖尿病肾病患者hEGF明显减低，当肾功能好转后，其hEGF浓度又可回升。认为，用RIA检验患者尿中hEGF浓度，可为临床检验肾功能提供一个参考指标。
Radioimmunoassay (RIA) was used to determine the concentration of morning urine hEGF in 60 patients with early diabetic nephropathy and the hEGF concentration in morning urine of 21 patients who were treated. The results showed that hEGF in patients with diabetic nephropathy Significantly reduced, when the renal function improved, its hEGF concentration can rise again. That the use of RIA test urinary hEGF concentration for clinical testing of renal function provides a reference index.