在西方国家,胃食管反流病是一种常见病,而且被认为是形成食管腺癌的主要危险因素[1]。胃-食管反流引起食管柱状上皮化生,这似乎是Barrett食管的起源,但并没有得到公认或者说没有用光学显微镜得到承认[2]。不能从病因方面加以预防,早期诊断就显得尤为重要。美国胃肠病学会提出Ba Gastroesophageal reflux disease is a common disease in western countries and is considered as a major risk factor for esophageal adenocarcinoma [1]. Gastric esophageal reflux induces esophageal columnar metaplasia, which appears to be the origin of the Barrett’s esophagus, but has not been recognized or not recognized by light microscopy [2]. Can not be prevented from the etiology, early diagnosis is particularly important. American Society of Gastroenterology Ba